“Anime Jeopardy!” is a fairly popular panel to hold at anime conventions, but many times they run into the same problems outside of the general problem of anime knowledge being an incredibly broad subject. First is that they tend to focus too much on specific shows, the second is that the questions tend to be about in-universe topics.
Just think about it: on actual “Jeopardy!” would you ever see a question about fiction like, “These are the number of windows in Dracula’s castle,” or “This man shook hands with a beggar in chapter 10 of such-and-such?” No, the questions do not reward simply having seen some shows more than others, but are more about accruing knowledge about the topics at hand and giving a few context clues.
So what would be the way to improve an “Anime Jeopardy!” panel? First, don’t assume too much about what are considered “easy” questions or “hard” ones. Second, make sure to give a fair amount of context clues as they would on actual “Jeopardy!” Third, there shouldn’t be too great a reward for people who have watched a particular show to death; that skews the results and makes it more difficult for more people to enjoy.
I’ve never run an Anime Jeopardy! panel myself so it may sound like I’m backseat panel-moderatin’, but I really think that if you follow these tips, your anime trivia panel will benefit from it, whether it’s in an existing game show format or not.
OGIUE MANIAX 
I agree with leaning away from the show-detail questions, but what would be good questions? And what do you mean not to assume too much about easy or hard questions? There needs to be a separation of the two for the multiple levels of questions.
I think some examples of what would be a good anime jeopardy questions (or technically answers) would help.
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Firstly, about the easy questions vs hard questions thing: What I mean is that depending on when you got into anime/the age you’re at/other variables, things that might be considered “throwaway questions” may very well not be. For instance, Sailor Moon might be common knowledge to a certain generation of fans but perhaps not a more current one. Reverse that with something like Naruto. That’s the kind of thing you have to be careful about.
Which leads me to the other part of your comment. You can still have questions that are more difficult, but no matter the obscurity you can soften the blow a bit by providing context clues. For example:
This 1972 manga and anime features teenager Akira transforming into demons so that he can fight other demons “man to man.”
-What is Devilman?
This long-time colleague of Hayao Miyazaki is probably best known for his World War II movie about a brother and sister.
-Who is Isao Takahata?
Here, even if you’re not sure of the exact propr response, there are little hints pushing you in the right direction. It doesn’t mean just anyone can get them, but it also means that you don’t mean complete knowledge or experience, just some recollection. And there tends to be more than one clue in the statement.
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